Ahmed Bettaieb is an assistant professor in the Department of Nutrition. Ahmed studied cancer biology and chemotherapy at the University of Quebec in Montreal Canada. He did postdoctoral training at the University of California studying obesity, diabetes and cardiovascular diseases. His previous training has afforded him a strong knowledge and technical background making him a well-trained scientist with the capabilities of producing more mechanistic advances in the treatment of metabolic disorders.
The long-term objectives of his research are: (1) provide a better understanding of the molecular and genetic mechanisms contributing to the development of metabolic diseases. (2) Exploit novel genes and therapeutic strategies aiming at reducing the overall burden of these diseases. Research publications- Bettaieb A, Hosein E, Chahed S, Abdulaziz A, Kucera HR, Gaikwad NW, Haj FG. Decreased adiposity and enhanced glucose tolerance in shikonin treated mice. Obesity (Silver Spring). 2015 Sep 16. doi: 10.1002/oby.21263.
Bettaieb A, Chahed S, Bachaalany S, Griffey S, Hammock BD, Haj FG. Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice. Mol Pharmacol. 2015 Aug;88(2):281-90.
Bettaieb A, Jiang JX, Sasaki Y, Chao TI, Kiss Z, Chen X, Tian J, Katsuyama M, Yabe-Nishimura C, Xi Y, Szyndralewiez C, Schröder K, Shah A, Brandes RP, Haj FG, Török NJ. Hepatocyte NADPH Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.Gastroenterology. 2015 Apr 14. pii: S0016-5085(15)00509-0.
Ahmed Bettaieb, Marcela Vazquez Prieto, Cecilia Rodriguez Lanzi, Roberto Miatello, Fawaz Haj, Cesar Fraga and Patricia Oteiza (2014). (-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress. Free Radical Biology and Medicine, 72C:247-256
Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD. Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain. Proceedings of the National Academy of Sciences, 112(29):9082-7. [PubMed]F1000Prime Recomended
Bora Inceoglu, Karen Wagner, Jun Yang, Ahmed Bettaieb, Nils Schebb, Fawaz Haj, Bruce Hammock (2012). Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes.Proceedings of the National Academy of Sciences, Jul 10;109(28):11390-5. [PubMed]F1000Prime Recommended
Bethany Cummings, Ahmed Bettaieb, James Graham, Kimber Stanhope, Riva Dill, Gregory Morton, Fawaz Haj and Peter Havel (2011). Subcutaneous administration of leptin normalizes fasting plasma glucose in obese type 2 diabetes UCD-T2DM rats. Proceedings of the National Academy of Sciences, August 30; 108(35):14670-5. [PubMed] F1000Prime Recommended
Ahmed’s contact information:
Department of Nutrition
302 Jessie W. Harris Building
1215 Cumberland Avenue
Knoxville, TN 37996-1920